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acta pharmacologica sinica (2026) 0  (TargetMol)


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    Structured Review

    TargetMol acta pharmacologica sinica (2026) 0
    Acta Pharmacologica Sinica (2026) 0, supplied by TargetMol, used in various techniques. Bioz Stars score: 95/100, based on 110 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/bioactive+compounds/Bioactive+Compound+Library/pm42875556-80-6-21
    Average 95 stars, based on 110 article reviews
    acta pharmacologica sinica (2026) 0 - by Bioz Stars, 2026-11
    95/100 stars

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    Related Articles

    other:

    Article Title: Cell Painting in activated cells illuminates phenotypic dark space and drug mechanisms of action
    Article Snippet: We obtained a library of 8,387 bioactive compounds (L4000-CUST, listed in Supplementary Data 1) from TargetMol.

    Article Title: Cell painting in activated cells illuminates phenotypic dark space and uncovers novel drug mechanisms of action
    Article Snippet: We obtained a library of 8,387 bioactive compounds (L4000-CUST), which were all the known bioactives available in solution format from TargetMol at the time of purchase by CSC (2022-05-03).

    Activity Assay:

    Article Title: A rapid sporozoite viability assay identifies leads and targetable enzymatic activities against the zoonotic Cryptosporidium parvum.
    Article Snippet: The mixtures were incubated at 25 ◦C for 3 h, and fluorescence signals were measured using a Cytation 5 Cell Imaging Multi-Mode Reader (BioTek Instruments) with excitation at 560 nm and emission at 590 nm. .. A library of 5000 bioactive compounds (Topscience, Shanghai, China) was screened for activity against C. parvum sporozoite viability using the luminescence ATP assay. ..

    Article Title: A rapid sporozoite viability assay identifies anti- Cryptosporidium parvum leads and targetable enzymatic activities in the invasive stage
    Article Snippet: The mixtures were incubated at 25 °C for 3 h, and fluorescence signals were measured using a Cytation 5 Cell Imaging Multi-Mode Reader (BioTek Instruments) with excitation at 560 nm and emission at 590 nm. .. A library of 5,000 bioactive compounds (Topscience, Shanghai, China) was screened for activity against C. parvum sporozoite viability using the luminescence ATP assay. ..

    ATP Assay:

    Article Title: A rapid sporozoite viability assay identifies leads and targetable enzymatic activities against the zoonotic Cryptosporidium parvum.
    Article Snippet: The mixtures were incubated at 25 ◦C for 3 h, and fluorescence signals were measured using a Cytation 5 Cell Imaging Multi-Mode Reader (BioTek Instruments) with excitation at 560 nm and emission at 590 nm. .. A library of 5000 bioactive compounds (Topscience, Shanghai, China) was screened for activity against C. parvum sporozoite viability using the luminescence ATP assay. ..

    Article Title: A rapid sporozoite viability assay identifies anti- Cryptosporidium parvum leads and targetable enzymatic activities in the invasive stage
    Article Snippet: The mixtures were incubated at 25 °C for 3 h, and fluorescence signals were measured using a Cytation 5 Cell Imaging Multi-Mode Reader (BioTek Instruments) with excitation at 560 nm and emission at 590 nm. .. A library of 5,000 bioactive compounds (Topscience, Shanghai, China) was screened for activity against C. parvum sporozoite viability using the luminescence ATP assay. ..

    Screening:

    Article Title: Type A asparagine synthetase in the zoonotic Cryptosporidium parvum (CpAsnA): Biochemical features and potential as a novel therapeutic target
    Article Snippet: .. Primary TSA screening was conducted for 5000 bioactive compounds (Topscience, Shanghai, China) at 40 μM. ..

    Drug discovery:

    Article Title: Targeting the CD4 + effector memory T cells re-expressing CD45RA suppressor galectin-7: a multi-omics-guided therapeutic strategy for idiopathic pulmonary fibrosis.
    Article Snippet: .. A library of approximately 20,000 bioactive compounds (TargetMol Bioactive Compound Library) was prepared using the LigPrep module (Schrödinger, LLC, New York, NY, 2021). ..



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